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Multilineage circuits of regenerative cell states.

Cell Stem Cell 30, 1397-1399 (2023)
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Regenerating the lungs' architecture after injury requires rebuilding its fibroelastic extracellular matrix scaffold. Konkimalla et al. establish that regenerative cell states (RCSs) of both epithelial and mesenchymal origin are functionally linked and indispensable for this process. Experimental ablation of RCSs causes organ degeneration, whereas their induction causes organ fibrosis.
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Publication type Article: Journal article
Document type Editorial
Language english
Publication Year 2023
HGF-reported in Year 2023
ISSN (print) / ISBN 1934-5909
e-ISSN 1875-9777
Journal Cell Stem Cell
Quellenangaben Volume: 30, Issue: 11, Pages: 1397-1399 Article Number: , Supplement: ,
Publisher Cell Press
Publishing Place Cambridge, Mass.
Reviewing status Peer reviewed
Institute(s) German Center for Lung Research (DZL)
Institute of Lung Health and Immunity (LHI)
POF-Topic(s) 80000 - German Center for Lung Research
30202 - Environmental Health
Research field(s) Lung Research
PSP Element(s) G-501800-810
G-501693-001
Scopus ID 85174930952
PubMed ID 37922876
Erfassungsdatum 2023-11-28