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Seeking satiety: From signals to solutions.
Sci. Transl. Med. 15:eadh4453 (2023)
Remedies for the treatment of obesity date to Hippocrates, when patients with obesity were directed to "reduce food and avoid drinking to fullness" and begin "running during the night." Similar recommendations have been repeated ever since, despite the fact that they are largely ineffective. Recently, highly effective therapeutics were developed that may soon enable physicians to manage body weight in patients with obesity in a manner similar to the way that blood pressure is controlled in patients with hypertension. These medicines have grown out of a revolution in our understanding of the molecular and neural control of appetite and body weight, reviewed here.
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Publication type
Article: Journal article
Document type
Review
Language
english
Publication Year
2023
HGF-reported in Year
2023
ISSN (print) / ISBN
1946-6234
e-ISSN
1946-6242
Journal
Science Translational Medicine
Quellenangaben
Volume: 15,
Issue: 723,
Article Number: eadh4453
Publisher
American Association for the Advancement of Science (AAAS)
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
POF-Topic(s)
30201 - Metabolic Health
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-502200-001
PubMed ID
37992155
Erfassungsdatum
2023-12-19