The chapter “Control of Systemic Metabolism by Astrocytes in the Brain” , written by Ophélia Le Thuc, Tim Gruber, Matthias H. Tschöp and Cristina García-Cáceres, was originally published electronically on the publisher’s internet portal without open access. With the authors’ decision to opt for Open Choice, the copyright of the chapter has been changed on 5 September 2023 to # the Authors 2021 and the chapter is forthwith distributed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/),which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence and indicate if changes were made. The images or other third-party material in this chapter are included in the chapter’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the chapter’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Funded by: Helmholtz Zentrum München.