Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
DOI
 |
|
Open Access Green as soon as Postprint is submitted to ZB.
In vivo NIR-II fluorescence imaging for biology and medicine.
Nat. Photonics, DOI: 10.1038/s41566-024-01391-5 (2024)
Owing to reduced light scattering and tissue autofluorescence, in vivo fluorescence imaging in the 1,000–3,000-nm near-infrared II (NIR-II) spectral range can afford non-invasive imaging at depths of millimetres within biological tissue. Infrared fluorescent probes labelled with antibodies or other targeting ligands also enable NIR-II molecular imaging at the single-cell level. Here we present recent developments in the design of fluorophores and probes emitting in the NIR-II window based on organic synthesis and nanoscience approaches. We also review advances in NIR-II wide-field and microscopy imaging modalities, with a focus on preclinical imaging and promising clinical translation case studies. Finally, we outline current issues and challenges for the wider adoption of NIR-II imaging in biomedical research and clinical imaging.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Review
Keywords
Carbon Nanotubes; Molecular Fluorophores; Microscopy; Deep; Systems; Window; Donor; Brain; Dye
ISSN (print) / ISBN
1749-4885
e-ISSN
1749-4893
Journal
Nature Photonics
Publisher
Nature Publishing Group
Publishing Place
Heidelberger Platz 3, Berlin, 14197, Germany
Reviewing status
Peer reviewed
Institute(s)
Helmholtz Pioneer Campus (HPC)
Grants
National Institutes of Health
U.S. Department of Health & Human Services | NIH | Center for Scientific Review (NIH Center for Scientific Review)
U.S. Department of Health & Human Services | NIH | Center for Scientific Review (NIH Center for Scientific Review)