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Traidl-Hoffmann, C. ; Afghani, J.* ; Akdis, C.* ; Akdis, M.* ; Aydin, H.* ; Bärenfaller, K.* ; Behrendt, H.* ; Bieber, T.* ; Bigliardi, P.L.* ; Bigliardi-Qi, M.* ; Bonefeld, C.M.* ; Bosch, S.* ; Brüggen, M.C.* ; Diemert, S.* ; Duchna, H.W.* ; Fähndrich, M.* ; Fehr, D.* ; Fellmann, M.* ; Frei, R.* ; Garvey, L.H.* ; Gharbo, R.* ; Gökkaya, M. ; Grando, K.* ; Guillet, C.* ; Guler, E.* ; Gutermuth, J.* ; Herrmann, N.* ; Hijnen, D.J.* ; Hülpüsch, C. ; Irvine, A.D.* ; Jensen-Jarolim, E.* ; Kong, H.H.* ; Koren, H.* ; Lang, C.C.V.* ; Lauener, R.* ; Maintz, L.* ; Mantel, P.Y.* ; Maverakis, E.* ; Möhrenschlager, M.* ; Müller, S.* ; Nadeau, K.* ; Neumann, A.U. ; O'Mahony, L.* ; Rabenja, F.R.* ; Renz, H.* ; Rhyner, C.* ; Rietschel, E.* ; Ring, J.* ; Roduit, C.* ; Sasaki, M.* ; Schenk, M.* ; Schröder, J.* ; Simon, D.* ; Simon, H.U.* ; Sokolowska, M.* ; Ständer, S.* ; Steinhoff, M.* ; Piccirillo, D.S.* ; Taïeb, A.* ; Takaoka, R.* ; Tapparo, M.* ; Teixeira, H.* ; Thyssen, J.P.* ; Traidl, S.* ; Uhlmann, M.* ; van de Veen, W.* ; van Hage, M.* ; Virchow, C.* ; Wollenberg, A.* ; Yasutaka, M.* ; Zink, A.* ; Schmid-Grendelmeier, P.*

Navigating the evolving landscape of atopic dermatitis: Challenges and future opportunities: The 4th Davos declaration.

Allergy, DOI: 10.1111/all.16247 (2024)
Publ. Version/Full Text DOI PMC
Open Access Gold (Paid Option)
Creative Commons Lizenzvertrag
The 4th Davos Declaration was developed during the Global Allergy Forum in Davos which aimed to elevate the care of patients with atopic dermatitis (AD) by uniting experts and stakeholders. The forum addressed the high prevalence of AD, with a strategic focus on advancing research, treatment, and management to meet the evolving challenges in the field. This multidisciplinary forum brought together top leaders from research, clinical practice, policy, and patient advocacy to discuss the critical aspects of AD, including neuroimmunology, environmental factors, comorbidities, and breakthroughs in prevention, diagnosis, and treatment. The discussions were geared towards fostering a collaborative approach to integrate these advancements into practical, patient-centric care. The forum underlined the mounting burden of AD, attributing it to significant environmental and lifestyle changes. It acknowledged the progress in understanding AD and in developing targeted therapies but recognized a gap in translating these innovations into clinical practice. Emphasis was placed on the need for enhanced awareness, education, and stakeholder engagement to address this gap effectively and to consider environmental and lifestyle factors in a comprehensive disease management strategy. The 4th Davos Declaration marks a significant milestone in the journey to improve care for people with AD. By promoting a holistic approach that combines research, education, and clinical application, the Forum sets a roadmap for stakeholders to collaborate to improve patient outcomes in AD, reflecting a commitment to adapt and respond to the dynamic challenges of AD in a changing world.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Allergy Treament ; Atopic Dermatitis ; Barrier ; Environment ; Hygiene Hypothesis; Global Allergy Forum; Human Mast-cells; Antimicrobial Peptides; Inflammatory Memory; Sensory Neurons; Nerve-fibers; Induced Itch; Skin; Histamine; Expression
ISSN (print) / ISBN 0105-4538
e-ISSN 1398-9995
Journal Allergy
Publisher Wiley
Publishing Place 111 River St, Hoboken 07030-5774, Nj Usa
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Environmental Medicine (IEM)