PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Zhang, S. ; Breitner-Busch, S. ; de'Donato, F.* ; Stafoggia, M.* ; Nikolaou, N. ; Aunan, K.* ; Peters, A. ; Schneider, A.E.

Heat and cause-specific cardiopulmonary mortality in Germany: A case-crossover study using small-area assessment.

Lancet Reg. Health-Eur. 46:101049 (2024)
Publ. Version/Full Text DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Background High temperatures have been associated with increased mortality, with evidence reported predominately in large cities and for total cardiovascular or respiratory deaths. This case-crossover study examined heat-related cause-specific fi c cardiopulmonary mortality and vulnerability factors using small-area data from Germany. Methods We analyzed daily counts of cause-specific fi c cardiopulmonary deaths from 380 German districts (2000-2016) - 2016) and daily mean temperatures estimated by spatial-temporal - temporal models. We applied conditional quasi-Poisson regression using distributed lag nonlinear models to examine heat effects during May-September - September in each district and random- effects meta-analysis to pool the district-specific fi c estimates. Potential individual- and district-level vulnerability factors were examined by subgroup analyses and meta-regressions, respectively. Findings Heat was associated with increased mortality risks for all cardiopulmonary sub-causes. The relative risk (RR) of total cardiovascular and respiratory mortality for a temperature increment from the 75th to the 99th percentile was 1.24 (95% confidence fi dence interval: 1.23, 1.26) and 1.34 (1.30, 1.38), respectively. The RRs of cardiovascular sub-causes ranged from 1.16 (1.13, 1.19) for myocardial infarction to 1.32 (1.29, 1.36) for heart failure. For respiratory sub- causes, the RR was 1.27 (1.22, 1.31) for COPD and 1.49 (1.42, 1.57) for pneumonia. We observed greater susceptibility related to several individual- and district-level characteristics, e.g., among females or in highly urbanized districts. Heat vulnerability factors remained consistent between urban and rural areas. Interpretation Our study highlights heat-related increases in cause-specific fi c cardiopulmonary mortality across Germany and identifies fi es key vulnerability factors, offering insights for improving public health practices to mitigate heat-related health impacts. Funding European Union's ' s Horizon 2020 research and innovation program; Helmholtz Associations Initiative and Networking Fund. Health 2024;46: Published https://doi.org/10. 1016/j.lanepe.2024. 101049
Impact Factor
Scopus SNIP
Altmetric
13.600
0.000
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Scientific Article
Keywords Temperature; Cardiovascular disease; Respiratory disease; Vulnerability factor; Urbanization; Air pollution; Greenness; Air-pollution; Temperature; Exposure; Metaanalysis; Pneumonia; Morbidity; Responses; Extremes; Outcomes; Weather
Language english
Publication Year 2024
HGF-reported in Year 2024
ISSN (print) / ISBN 2666-7762
e-ISSN 2666-7762
Journal The Lancet Regional Health - Europe
Quellenangaben Volume: 46, Issue: , Pages: , Article Number: 101049 Supplement: ,
Publisher Elsevier
Publishing Place Radarweg 29, 1043 Nx Amsterdam, Netherlands
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
POF-Topic(s) 30202 - Environmental Health
Research field(s) Genetics and Epidemiology
PSP Element(s) G-504000-001
G-504000-010
Grants Helmholtz Associations Initiative and Networking Fund
European Union
DOI 10.1016/j.lanepe.2024.101049
WOS ID 001310700100001
PubMed ID 39290807
Erfassungsdatum 2024-09-26
[➜Report correction]