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Lonardo, A.* ; Stefan, N. ; Mantovani, A.*

Widening research horizons on metabolic dysfunction-associated steatotic liver disease and cancer.

Trends Endocrinol. Metab., DOI: 10.1016/j.tem.2024.12.009 (2025)

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Open Access Green as soon as Postprint is submitted to ZB.

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Liver fibrosis and biological sex variably modulate the risks of hepatocellular carcinoma (HCC) and extrahepatic cancers (EHCs) arising in the context of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we highlight how these variables may have implications in the setting of chemoprevention and precision medicine approaches in MASLD and guide additional research.

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Publication type Article: Journal article

Document type Other: Opinion

Corresponding Author

ISSN (print) / ISBN 1043-2760

e-ISSN 1879-3061

Journal Trends in Endocrinology and Metabolism

Publisher Elsevier

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Diabetes Research and Metabolic Diseases (IDM)