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Kobold, S.

RORing CAR T cells in solid and hematologic cancers: Same but different.

Clin. Cancer Res. 31, 437-438 (2025)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
A recent phase I clinical study tested anti-ROR1 chimeric antigen receptor (CAR) T cells in patients with chronic lymphocytic leukemia, non–small cell lung cancer, and triple-negative breast cancer. The product could be safely administered and had activity in chronic lymphocytic leukemia but less so in non–small cell lung cancer and triple-negative breast cancer.
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Publication type Article: Journal article
Document type Comment, Opinion
Language english
Publication Year 2025
HGF-reported in Year 2025
ISSN (print) / ISBN 1078-0432
e-ISSN 1557-3265
Journal Clinical Cancer Research
Quellenangaben Volume: 31, Issue: 3, Pages: 437-438 Article Number: , Supplement: ,
Publisher American Association for Cancer Research (AACR)
Publishing Place 615 Chestnut St, 17th Floor, Philadelphia, Pa 19106-4404 Usa
Reviewing status Peer reviewed
Institute(s) Unit for Clinical Pharmacology (KKG-EKLiP)
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Immune Response and Infection
PSP Element(s) G-522100-001
Grants The m4 Award of the Bavarian Ministry for Economic Affairs
Bavarian Research Foundation (BAYCELLATOR)
Go-Bio-Initiative
Monika Kutzner Foundation for Cancer Research
Institutional Strategy LMUexcellent of LMU Munich
Hector Foundation
Ernst Jung Stiftung
Wilhelm-Sander-Stiftung
German Cancer Aid (AvantCAR.de)
Else Kroener-Fresenius-Stiftung (IOLIN)
Marie Sklodowska-Curie Training Network for Optimizing Adoptive T Cell Therapy of Cancer by European Union
Melanoma Research Alliance
Elite Network of Bavaria
Deutsche Forschungsgemeinschaft
Bruno and Helene Joester Foundation (360degrees CAR)
Bundesministerium fuer Bildung und Forschung
European Research Council

Deutsche Jose Carreras Leukaemie Stiftung
SFB-TRR-Fritz-Bender Foundation
Bavarian Cancer Research Center (TANGO)
DOI 10.1158/1078-0432.CCR-24-3688
WOS ID 001413069400014
Scopus ID 85216951929
PubMed ID 39625823
Erfassungsdatum 2025-04-09
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