Clues to quality of journals
Open Access Policy of Helmholtz Association 2016
CC Licencences
Publication Metrics
Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Statistics (last 5 years)
OA Publications
Submit Publication
Import publication from...
Report missing publication
Contact persons
Help
Text
Endnote (RIS)
BibTeX
Publ. Version/Full Text
DOI
PMC
 |
Open Access Gold |
|
as soon as is submitted to ZB.
Personalized joint replacement: Landmark-free morphometric analysis of distal radii.
J Funct. Morphol. Kinesiol. 10:71 (2025)
Background: Fractures of the distal radius are common, particularly among young men and elderly women, often leading to painful wrist arthritis, especially if the joint surface has been affected. Traditional treatments of the wrist, such as full or partial wrist fusion, limit movement, and common wrist prostheses have high complication rates. Regenerative medicine and 3D bioprinting offer the potential for personalized joint replacements. Methods: This study evaluates using the contralateral radius as a template for creating customized distal radius prostheses. Bilateral CT scans of healthy wrists were analyzed to assess the shape and symmetry of the distal radius using a landmark-free morphometric method. Instead of comparing defined landmarks, the entire surface of the radius is analyzed employing dense point- and deformation-based morphometry to detect subtle morphological differences, providing an unbiased and more accurate comparison of the overall deformations in the distal radii. Results: results show strong intraindividual symmetry in joint surfaces. Interindividual comparisons revealed significant morphological variations, particularly gender-specific differences. Conclusions: These findings support the use of the contralateral radius as a template for the replaced side. At the same time, the interindividual results endorse the approach of pursuing personalized prostheses as the optimal replacement for distal joint surfaces. The increasing improvement of 3D-printed prostheses promises new methods for better outcomes in distal radius arthrosis after intraarticular fractures. Further research into clinical applications and biocompatible 3D printing materials is recommended.
Impact Factor
Scopus SNIP
Altmetric
2.500
0.951
Annotations
Special Publikation
Hide on homepage
Publication type
Article: Journal article
Document type
Scientific Article
Keywords
3d-printed Prostheses ; Ct ; Anatomy Of The Wrist ; Distal Radius ; Hand Surgery ; Landmark-free Morphometry ; Mirror Symmetry; Articular Fractures; Arthroplasty; Fixation; Outcomes; End
Language
english
Publication Year
2025
HGF-reported in Year
2025
ISSN (print) / ISBN
2411-5142
e-ISSN
2411-5142
Quellenangaben
Volume: 10,
Issue: 1,
Article Number: 71
Publisher
MDPI
Publishing Place
Mdpi Ag, Grosspeteranlage 5, Ch-4052 Basel, Switzerland
Reviewing status
Peer reviewed
Institute(s)
Institute for Machine Learning in Biomed Imaging (IML)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-507100-001
WOS ID
001482835200001
Scopus ID
105001425485
PubMed ID
40137323
Erfassungsdatum
2025-05-09