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Hofmann, S.M.

Geschlechtersensible Aspekte von Diabetes mellitus Typ 2.Präzisionsmedizin der Zukunft in der Diabetologie.

Sex- and gender-specific aspects of type 2 diabetes mellitus: The future of precision medicine in diabetology.

Diabetologie 21, 523–531 (2025)

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The prevalence of type 2 diabetes is increasing in both sexes, with men usually being diagnosed at a younger age and with a lower body fat mass. Women often have a higher risk factor profile at diagnosis, particularly in relation to obesity and psychosocial stress. Pregnancy and menopause also increase the cardiometabolic risk in women. Women have a higher relative risk of cardiovascular disease and mortality compared to men. Gender-specific prevention strategies are still under development and require a better understanding of differences and mechanisms. Differing health effects of diabetes in men and women require personalized prevention and treatment strategies for optimal care.

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