PuSH - Publication Server of Helmholtz Zentrum München: Evaluation of spinal cor blood supply with hyperspectral imaging of the paraspinous musculature during staged endovascular repair of thoracoabdominal aortic aneurysm: A sub-study of the prospective multicenter PAPA-ARTiS trial.

Navigation

Home

Deutsch

Research

Advanced Search

Browse by ...

... Journal

... Publication Type

... Research Data

... Publication Year

Publication overview

Support & Contact

Contact persons

Help

Data protection

Winther, B. ; Branzan, D. ; Etz, C.D.* ; Geisler, A.A.* ; Steiner, S. ; Winther, H.* ; Meixner, R. ; Jiménez-Muñoz, M. ; Kohler, H.* ; Scheinert, D.* ; Schmidt, A.*

Evaluation of spinal cor blood supply with hyperspectral imaging of the paraspinous musculature during staged endovascular repair of thoracoabdominal aortic aneurysm: A sub-study of the prospective multicenter PAPA-ARTiS trial.

J. Clin. Med. 14:3188 (2025)

Publ. Version/Full Text

DOI

PMC

	Open Access Gold

Abstract
Metrics
Extra information

Background/Objectives: Our aim was to assess the feasibility of hyperspectral imaging (HSI) to detect changes in tissue oxygenation (StO₂) of the back, as non-invasive spinal cord collateral network (CN) monitoring during staged endovascular repair (ER) of thoracoabdominal aortic aneurysm (TAAA). Methods: Between September 2019 and June 2021, 20 patients were treated for TAAA and underwent HSI. They were randomized 1:1 to minimally invasive staged segmental artery coil embolization (MIS2ACE) (n = 10) and staged stentgraft implantation (n = 10) as priming methods. HSI of paravertebral regions was taken during each procedure and up to 10 days after. The primary endpoint was the identification of StO₂ changes after ER of TAAA. Results: TAAA Crawford Type II (n = 17) and Type III (n = 3) were treated. After stentgrafting, StO₂ increased immediately (p < 0.001), followed by a decrease after 5 days (p < 0.001) and 10 days (p = 0.028). StO₂ was significantly higher in the thoracic compared to the lumbar region. There was no significant difference between MIS2ACE and the first stentgrafting for StO₂ (p = 0.491). Following MIS2ACE, definitive ER caused a significant decrease in StO₂ after 5 days (p = 0.021), which recovered to baseline after 10 days (p = 0.130). After stentgraft priming, definitive ER caused a significant decrease in StO₂ after 24 h (p = 0.008), which did not return to baseline after 5 (p < 0.001) and 10 days (p = 0.019). Conclusions: HSI detected significant changes in StO₂ in the thoracic and lumbar paravertebral regions during ER of TAAA. These preliminary data suggest the efficacy of MIS2ACE in priming the CN before ER of TAAA.

Altmetric

Additional Metrics?

[➜Log in]

Edit extra informations Login

Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Aortic Aneurysm ; Collateral Network ; Endovascular Repair ; Hyperspectral Imaging ; Spinal Cord Ischemia; Near-infrared Spectroscopy; Collateral Network Concept; Risk-factors; Ischemia

ISSN (print) / ISBN 2077-0383

e-ISSN 2077-0383

Journal Journal of Clinical Medicine

Quellenangaben Volume: 14, Issue: 9, Article Number: 3188

Publisher MDPI

Publishing Place Basel

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Helmholtz Institute for Metabolism, Obesity and Vascular Research (HI-MAG)
CF Statistical Consulting (CF-STATCON)