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Dendritic cells in experimental renal inflammation - Part I.
Nephron Exp. Nephrol 119, E83-E90 (2011)
Publ. Version/Full Text Volltext
DOI
PMC
Dendritic cells (DCs) are bone marrow-derived professional antigen-presenting cells that act as master regulators of acquired and innate immune responses. While descriptions of cells with dendritic morphology in rodent kidneys date back to the early 1970s, a network of DCs in the mouse kidney has only recently been described. DCs acquire distinct phenotypic and functional characteristics depending on the microenvironment and the disease stages. Concomitantly, their communication with cells of the adaptive immunity might have tissue-protective or tissue-deleterious consequences. This review summarizes results from recent studies on the role of DCs in experimental renal inflammation.
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Publication type
Article: Journal article
Document type
Review
Keywords
Dendritic cells; Glomerulonephritis; Interstitial inflammation; Experimental renal inflammation; PERIPHERAL LYMPHOID ORGANS; ISCHEMIA-REPERFUSION INJURY; ACUTE KIDNEY INJURY; LUPUS NEPHRITIS; HUMAN BLOOD; IDENTIFICATION; MICE; MOUSE; HETEROGENEITY; INTERFERON
ISSN (print) / ISBN
1660-2129
e-ISSN
0028-2766
Quellenangaben
Volume: 119,
Issue: 4,
Pages: E83-E90
Publisher
Karger
Publishing Place
Basel
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Molecular Immunology (IMI)