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Open Access Green as soon as Postprint is submitted to ZB.
Selective detection of superoxide by benzoselenadiazole based BODIPY probe: Synthesis and biological activity.
Main Group Chem. 23, 473-482 (2025)
New benzoselenadiazole based BODIPY probe was synthesized and characterized with spectroscopic techniques like 1H, 13C, 77Se and mass spectrometry. The fluorescence of the probe quenched in the presence of superoxide ion, showing “Turn-off” response without interfering with other ROS even at higher concentrations. The detection limit was found to be 21.28μM. Kinetic study reveal the fast reaction between the probe and superoxide with good photostability. Also, the probe was studied for biological activity and found to be good agent for anti-inflammatory and antioxidant activities.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Anti-inflammatory Activity ; Antioxidant Assay ; Benzoselenadiazole ; Bodipy ; Superoxide ; Turn-off Response; Glutathione-peroxidase; Cancer Chemoprevention; Fluorescent-probe; In-vitro; Selenium; Derivatives; Peroxynitrite; Chemotherapy; Recognition; Mechanisms
ISSN (print) / ISBN
1024-1221
e-ISSN
1745-1167
Journal
Main Group Chemistry
Quellenangaben
Volume: 23,
Issue: 4,
Pages: 473-482
Publisher
Sage
Publishing Place
2455 Teller Rd, Thousand Oaks, Ca 91320 Usa
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
Grants
New Delhi
Science and Engineering Research Board (SERB)
Science and Engineering Research Board (SERB)