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Tirzepatide differentially affects body weight in mice and humans.
Nat. Rev. Endocrinol., DOI: 10.1038/s41574-025-01139-3 (2025)
Advances in biomedical research often result from a straightforward formula: a good working hypothesis, a set of dedicated investigators, and access to calorimetric chambers and a laboratory scale. The success of this approach has again been demonstrated in a new Cell Metabolism report showing that tirzepatide induces weight loss through partially distinct mechanisms in mice and humans.
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Publication type
Article: Journal article
Document type
Comment, Opinion
Language
english
Publication Year
2025
HGF-reported in Year
2025
ISSN (print) / ISBN
1759-5029
e-ISSN
1759-5037
Journal
Nature Reviews - Endocrinology
Publisher
Nature Publishing Group
Publishing Place
New York, NY
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
POF-Topic(s)
90000 - German Center for Diabetes Research
30201 - Metabolic Health
30201 - Metabolic Health
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-501900-221
G-502200-001
G-502200-001
WOS ID
001505025500001
Scopus ID
105007802728
PubMed ID
40490496
Erfassungsdatum
2025-06-16