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Chronopoulos, J.* ; Crespo, M. ; Chavakis, T.

Central trained immunity in the context of bladder cancer immunotherapy.

Cancer Cell 43, 1394-1396 (2025)
DOI PMC
Two articles in Immunity and Cancer Cell describe that bladder cancer immunotherapy with Bacillus Calmette-Guerin (BCG) alone or in combination with β-glucan, another agonist of trained immunity (TRIM), involves reprogramming of bone marrow (BM) hematopoiesis. These findings provide additional evidence of the therapeutic potential of BM-mediated TRIM against cancer.
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Publication type Article: Journal article
Document type Comment, Opinion
ISSN (print) / ISBN 1535-6108
e-ISSN 1878-3686
Journal Cancer Cell
Quellenangaben Volume: 43, Issue: 8, Pages: 1394-1396 Article Number: , Supplement: ,
Publisher Cell Press
Publishing Place Cambridge, Mass.
Reviewing status Peer reviewed
Institute(s) Institute of Pancreatic Islet Research (IPI)