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Central trained immunity in the context of bladder cancer immunotherapy.
Cancer Cell 43, 1394-1396 (2025)
Two articles in Immunity and Cancer Cell describe that bladder cancer immunotherapy with Bacillus Calmette-Guerin (BCG) alone or in combination with β-glucan, another agonist of trained immunity (TRIM), involves reprogramming of bone marrow (BM) hematopoiesis. These findings provide additional evidence of the therapeutic potential of BM-mediated TRIM against cancer.
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Publication type
Article: Journal article
Document type
Comment, Opinion
Language
english
Publication Year
2025
HGF-reported in Year
2025
ISSN (print) / ISBN
1535-6108
e-ISSN
1878-3686
Journal
Cancer Cell
Quellenangaben
Volume: 43,
Issue: 8,
Pages: 1394-1396
Publisher
Cell Press
Publishing Place
Cambridge, Mass.
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
POF-Topic(s)
90000 - German Center for Diabetes Research
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-502600-008
WOS ID
001561791100004
Scopus ID
105009697959
PubMed ID
40614740
Erfassungsdatum
2025-09-30