PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Banks, A.S.* ; Allison, D.B.* ; Alquier, T.* ; Ansarullah* ; Austad, S.N.* ; Auwerx, J.* ; Ayala, J.E.* ; Baur, J.A.* ; Carobbio, S.* ; Churchill, G.A.* ; Dall, M.* ; de Cabo, R.* ; Donato, J.* ; Dragano, N.R.V. ; Elias, C.F.* ; Ferrante, A.W.* ; Finck, B.N.* ; Galgani, J.E.* ; Gerhart-Hines, Z.* ; Goodyear, L.J.* ; Grobe, J.L.* ; Gupta, R.K.* ; Habegger, K.M.* ; Hartig, S.M.* ; Hevener, A.L.* ; Heymsfield, S.B.* ; Holman, C.D.* ; Hrabě de Angelis, M. ; James, D.E.* ; Kazak, L.* ; Kim, J.B.* ; Klingenspor, M.* ; Kong, X.* ; Kooijman, S.* ; Lantier, L.* ; Lloyd, K.C.K.* ; Lo, J.C.* ; Lodhi, I.J.* ; MacLean, P.S.* ; McGuinness, O.P.* ; Medina-Gomez, G.* ; Mirmira, R.G.* ; Morrison, C.D.* ; Morton, G.J.* ; Müller, T.D. ; Ogawa, Y.* ; Pajuelo-Reguera, D.* ; Potthoff, M.J.* ; Qi, N.* ; Reitman, M.L.* ; Rensen, P.C.N.* ; Rozman, J.* ; Rutkowsky, J.M.* ; Sakamoto, K.* ; Scherer, P.E.* ; Schwartz, G.J.* ; Sedlacek, R.* ; Selloum, M.* ; Shaikh, S.R.* ; Chen, S.* ; Shulman, G.I.* ; Škop, V.* ; Soukas, A.A.* ; Speakman, J.R.* ; Spiegelman, B.M.* ; Steinberg, G.R.* ; Svensson, K.J.* ; Thyfault, J.P.* ; Tiganis, T.* ; Titchenell, P.M.* ; Turner, N.* ; Velloso, L.A.* ; Vidal-Puig, A.* ; Ward, C.S.* ; Williams, A.S.* ; Wolfrum, C.* ; Xu, A.W.* ; Xu, Y.* ; Zierath, J.R.*

A consensus guide to preclinical indirect calorimetry experiments.

Nat. Metab. 7, 1765-1780 (2025)
Publ. Version/Full Text DOI PMC
Closed
Open Access Green as soon as Postprint is submitted to ZB.
Understanding the complex factors influencing mammalian metabolism and body weight homeostasis is a long-standing challenge requiring knowledge of energy intake, absorption and expenditure. Using measurements of respiratory gas exchange, indirect calorimetry can provide non-invasive estimates of whole-body energy expenditure. However, inconsistent measurement units and flawed data normalization methods have slowed progress in this field. This guide aims to establish consensus standards to unify indirect calorimetry experiments and their analysis for more consistent, meaningful and reproducible results. By establishing community-driven standards, we hope to facilitate data comparison across research datasets. This advance will allow the creation of an in-depth, machine-readable data repository built on shared standards. This overdue initiative stands to markedly improve the accuracy and depth of efforts to interrogate mammalian metabolism. Data sharing according to established best practices will also accelerate the translation of basic findings into clinical applications for metabolic diseases afflicting global populations.
Impact Factor
Scopus SNIP
Altmetric
20.800
0.000
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Review
Keywords Resting Energy-expenditure; Cold-induced Thermogenesis; Diet-induced Obesity; Delta T-cells; Metabolic-rate; Skeletal-muscle; Adipose-tissue; Mouse Model; Body-temperature; Heart-rate
Language english
Publication Year 2025
HGF-reported in Year 2025
ISSN (print) / ISBN 2522-5812
e-ISSN 2522-5812
Journal Nature metabolism
Quellenangaben Volume: 7, Issue: 9, Pages: 1765-1780 Article Number: , Supplement: ,
Publisher Springer
Publishing Place London
Reviewing status Peer reviewed
Institute(s) Institute of Experimental Genetics (IEG)
Institute of Diabetes and Obesity (IDO)
POF-Topic(s) 30201 - Metabolic Health
90000 - German Center for Diabetes Research
Research field(s) Genetics and Epidemiology
Helmholtz Diabetes Center
PSP Element(s) G-500692-001
G-500600-001
G-501900-221
Grants FAPESP
NIH
DOI 10.1038/s42255-025-01360-4
WOS ID 001578286300002
Scopus ID 105016909395
PubMed ID 40993210
Erfassungsdatum 2025-09-25
[➜Report correction]