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Sleep related movement disorders: What's new and changing clinical practice.
J. Sleep Res., DOI: 10.1111/jsr.70210:e70210 (2025)
Restless legs syndrome (RLS) is a common sensorimotor disorder, and the most common sleep-related movement disorder with a prevalence of up to 15% in the European and US population. This review addresses key aspects of RLS, focusing on novel data that have or will likely have an impact on clinical practice. These include novel insights into pathophysiology and motor activity during sleep, with a key focus on implications for RLS treatment. Along this line, we discuss the problem of augmentation before introducing new treatment paradigms and insights into new drug targets from genetics. Besides RLS, restless sleep disorder, neck myoclonus, fragmentary myoclonus, propriospinal myoclonus at the wake-sleep transition, and facio-mandibular myoclonus are discussed. This review provides an overview of the most recent insights into sleep-related movement disorders, and of how they are changing clinical practice.
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Publication type
Article: Journal article
Document type
Review
Keywords
Rls ; Rsdlmm ; Large Muscle Group Movements ; Restless Legs Syndrome ; Restless Sleep Disorder
ISSN (print) / ISBN
0962-1105
e-ISSN
0962-1105
Journal
Journal of Sleep Research
Quellenangaben
Article Number: e70210
Publisher
Wiley
Publishing Place
Oxford
Reviewing status
Peer reviewed
Institute(s)
Institute of Neurogenomics (ING)