Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
Publ. Version/Full Text
DOI
PMC
 |
Open Access Hybrid |
|
as soon as is submitted to ZB.
Targeted treatment in asthma - opportunities and challenges.
J. Allergy Clin. Immunol. Pract. 14, 76-93 (2025)
This review summarizes the key insights and future directions on targeted asthma treatment discussed during the 2025 Expert Meeting supported by the Central and Southern European Allergy and Asthma Alliance (CSEA3). Targeted treatment in asthma is becoming an attainable goal for selected patients but is not yet established as a standard asthma care pathway. The expert panel identified four key priorities to advance targeted asthma management: (1) Defining remission-a universally accepted, evidencebased definition is needed to guide clinical practice and guideline development. (2) The management of mild asthma guided by patient stratification according to asthma pathogenetic pathways (endotype) and risk profile may enable more tailored therapy and better outcomes. (3) Biomarker discovery and validation-research must prioritize predictive biomarkers that are easy to measure at the point of care, supported by innovative trials that combine precision immunology and machine learning. (4) Optimizing implementation and addressing the barriers to adopting stratified care, including limited resources and cost-effectiveness concerns, must be addressed. Digital tools offer promise but require further validation. Coordinated efforts are essential to translate advances in personalized asthma treatment into better outcomes and more sustainable care, particularly in resource-limited settings.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Review
Keywords
Asthma ; Biologics ; Biomarker ; Endotype ; Mild Asthma ; Personalized Medicine ; Remission ; Targeted Treatment; Exhaled Nitric-oxide; Allergen Immunotherapy; Budesonide-formoterol; Blood Eosinophils; Lung-function; Inhaled Corticosteroids; Airway Inflammation; Sputum Eosinophils; Mild Asthma; Adults
ISSN (print) / ISBN
2213-2198
e-ISSN
2213-2201
Quellenangaben
Volume: 14,
Issue: 1,
Pages: 76-93
Publisher
Elsevier
Publishing Place
Amsterdam [u.a.]
Reviewing status
Peer reviewed
Institute(s)
Institute of Lung Health and Immunity (LHI)
Grants
Department of Allergology Ioannina, Ioannina, Greece
Kaunas, Lithuania
University Hospital Centre Zagreb, Zagreb, Croatia
Institute of Clinical Immunology and Allergy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Clinic of Chest Diseases
Laura Malinauskien_e: Pulmonology and Allergology Center
Martin, Slovakia
Kaunas, Lithuania
University Hospital Centre Zagreb, Zagreb, Croatia
Institute of Clinical Immunology and Allergy, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
Clinic of Chest Diseases
Laura Malinauskien_e: Pulmonology and Allergology Center
Martin, Slovakia