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Huang, W.* ; Li, T.* ; Masselot, P.* ; Xu, R.* ; Gasparrini, A.* ; Sera, F.* ; Bell, M.L.* ; Hashizume, M.* ; Breitner-Busch, S. ; Tong, S.* ; Kan, H.* ; Yang, Z.* ; Zhang, Y.* ; Yu, W.* ; Yu, P.* ; Zhou, S.* ; Sun, Q.* ; Zhang, J.* ; Lavigne, E.* ; Madureira, J.* ; Guo, Y.L.* ; Gaio, V.* ; Li, S.* ; Guo, Y.*

Improved global air quality health index reveals ozone and nitrogen dioxide as main drivers of air-pollution-related acute mortality.

One Earth 8:101488 (2025)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Ambient air pollutants are leading contributors to global mortality. Despite the well-established risks, most studies have relied on single-pollutant models in limited regions, leaving the combined effects and individual contributions of pollutants unclear, particularly across countries. Here, we integrate daily mortality and air pollutant (nitrogen dioxide [NO2], ozone [O3], fine particulate matter, and sulfur dioxide) data from 482 cities in 12 countries/territories from 1998 to 2021 to assess the joint mortality risks and identify the main contributing pollutant through an air quality health index of multi-pollutant constrained groupwise additive models (AQHI-Multi). AQHI-Multi outperformed commonly used air quality indices in capturing the overall mortality risks. O3 and NO2 were the leading contributors (accounting for over 70% across countries/territories), with O3's share increasing slightly to moderately in most countries/territories. These findings highlight the need for developing air quality indices using advanced multi-pollutant models and the emerging global significance of targeted control of O3 and NO2.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Acute Mortality Risks ; Air Pollution ; Air Quality Health Index ; Multi-country Study ; Multi-pollutant Model ; Relative Risk Contributions ; Risk Communication; Associations; Risk; Urban
ISSN (print) / ISBN 2590-3330
e-ISSN 2590-3322
Journal One Earth
Quellenangaben Volume: 8, Issue: 11, Pages: , Article Number: 101488 Supplement: ,
Publisher Elsevier
Publishing Place 50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
Grants Science and Technology Commission of Shanghai Municipality
Australian National Health and Medical Research Council
China Scholarship Council funds
Monash Graduate Scholarship
Monash International Tuition Scholarship
NHMRC e-Asia Joint Research Program grant
VicHealth Postdoctoral Research Fellowships
Monash Faculty of Medicine Nursing and Health Science (FMNHS) Early Career Postdoctoral Fellowships 2023
EU
Wellcome-funded project BREATHE
Medical Research Council, United Kingdom
Natural Environment Research Council United Kingdom
Japan Science and Technology Agency as part of SICORP
Australian Research Council