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One small molecule for man, one giant leap for mankind with obesity.

Med. 6:100924 (2025)
DOI PMC
The ATTAIN-1 trial launches a new era in obesity care. Orforglipron, the first oral small-molecule GLP-1 receptor agonist to complete a phase 3 clinical trial, delivers meaningful reductions in body weight and improvements in metabolic health. This advancement moves beyond peptide-based injectables, paving the way for potent obesity therapies that are simpler, more affordable, and accessible to millions worldwide.
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Publication type Article: Journal article
Document type Editorial
ISSN (print) / ISBN 2666-6359
e-ISSN 2666-6340
Journal Med (N Y)
Quellenangaben Volume: 6, Issue: 12, Pages: , Article Number: 100924 Supplement: ,
Publisher Cell Press
Reviewing status Peer reviewed