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Open Access Green as soon as Postprint is submitted to ZB.
A sex-specific brake on liver oestrogen signalling.
Nat. Metab. 8, 8-9 (2026)
Sex profoundly shapes liver metabolism, with oestrogens conferring protection against metabolic liver disease. In this study, Yang, Wang and colleagues identify the orphan G protein-coupled receptor GPR110 as a liver-specific brake on oestrogen signalling, bridging GPCR and nuclear receptor pathways, thus pointing to GPR110 as a target for sex-specific therapy in liver disease.
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Publication type
Article: Journal article
Document type
Editorial
ISSN (print) / ISBN
2522-5812
e-ISSN
2522-5812
Journal
Nature metabolism
Quellenangaben
Volume: 8,
Issue: 1,
Pages: 8-9
Publisher
Springer
Publishing Place
London
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)
Grants
European Foundation for the Study of Diabetes
DFG
DFG