PuSH - Publication Server of Helmholtz Zentrum München: Embryo transfer following IVF alters susceptibility to metabolic phenotypes in male mouse offspring compared to naturally conceived offspring.

Navigation

Home

Deutsch

Research

Advanced Search

Browse by ...

... Journal

... Publication Type

... Research Data

... Publication Year

Publication overview

Support & Contact

Contact persons

Help

Data protection

Laurent, K. ; Hoffmann, S. ; Marschall, S. ; Richter, K.B. ; Teperino, R. ; Hrabě de Angelis, M. ; Skerrett-Byrne, D.A. ; Beckers, J.

Embryo transfer following IVF alters susceptibility to metabolic phenotypes in male mouse offspring compared to naturally conceived offspring.

Reprod. Fertility 7:RAF260031 (2026)

Publ. Version/Full Text

Postprint

DOI

PMC

	Open Access Gold

Abstract
Metrics
Extra information

Lay summary The aim of this study is to highlight potential differences between embryos conceived naturally and those conceived via in vitro fertilisation (IVF). While the current scientific literature generally assumes that differences between these two modes of conception exist, many studies do not provide detailed phenotypic data, e.g. bodyweight, blood glucose and other observational metabolic health parameters. In addition, comparisons are often complicated by variations in choosing different strains of foster mothers to carry embryos. By addressing these limitations, our short summary and overview provide a well-defined comparison within a controlled experimental setup including a high-fat diet feeding period as metabolic challenge. We make the resulting data publicly available to offer a reference point for researchers using a specific mouse strain as fosters and to improve transparency regarding the specific differences in metabolic health observed between natural conception and IVF in this context.

Altmetric

Additional Metrics?

[➜Log in]

Edit extra informations Login

Publication type Article: Journal article

Document type Scientific Article

Keywords Offspring ; Phenotype ; Embryo Transfer ; Embryo ; Single Embryo Transfer ; Maternal Effect

ISSN (print) / ISBN 2633-8386

e-ISSN 2633-8386

Journal Reproduction and Fertility

Quellenangaben Volume: 7, Issue: 2, Article Number: RAF260031

Publisher Bioscientifica Ltd.

Publishing Place Starling House, 1600 Bristol Parkway N, Bristol, England

Reviewing status Peer reviewed

Institute(s) Institute of Experimental Genetics (IEG)

Grants DZD e.V
National Health and Medical Research Council (NHMRC) Emerging Leadership Fellowship