OpenSSL SSL_connect: Connection reset by peer in connection to v2.sherpa.ac.uk:443 PuSH - Publication Server of Helmholtz Zentrum München: A guide to analysis of mouse energy metabolism.

PuSH - Publication Server of Helmholtz Zentrum München

Tschöp, M.H. ; Speakman, J.R.* ; Arch, J.R.S.* ; Auwerx, J.* ; Brüning, J.C.* ; Chan, L.* ; Eckel, R.H.* ; Farese, R.V.* ; Galgani, J.E.* ; Hambly, C.* ; Herman, M.A.* ; Horvath, T.L.* ; Kahn, B.B.* ; Kozma, S.C.* ; Maratos-Flier, E.* ; Müller, T.D. ; Münzberg, H.* ; Pfluger, P.T. ; Plum, L.* ; Reitman, M.L.* ; Rahmouni, K.* ; Shulman, G.I.* ; Thomas, G.* ; Kahn, C.R.* ; Ravussin, E.*

A guide to analysis of mouse energy metabolism.

Nat. Methods 9, 57-63 (2012)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
We present a consolidated view of the complexity and challenges of designing studies for measurement of energy metabolism in mouse models, including a practical guide to the assessment of energy expenditure, energy intake and body composition and statistical analysis thereof. We hope this guide will facilitate comparisons across studies and minimize spurious interpretations of data. We recommend that division of energy expenditure data by either body weight or lean body weight and that presentation of group effects as histograms should be replaced by plotting individual data and analyzing both group and body-composition effects using analysis of covariance (ANCOVA).
Altmetric
Additional Metrics?
[➜Log in]
Edit extra informations Login
Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Mice; Obesity; Energy Metabolism; Environment; Body Composition; CHRONIC SOCIAL STRESS; DIET-INDUCED OBESITY; FAT-FREE MASS; BODY-COMPOSITION; LABORATORY MICE; FOOD-INTAKE; EXPENDITURE; TISSUE; AGE; BEHAVIOR
ISSN (print) / ISBN 1548-7091
e-ISSN 1548-7105
Journal Nature Methods
Quellenangaben Volume: 9, Issue: 1, Pages: 57-63 Article Number: , Supplement: ,
Publisher Nature Publishing Group
Publishing Place New York, NY
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Diabetes and Obesity (IDO)