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The lytic phase of Epstein-Barr virus requires a viral genome with 5-methylcytosine residues in CpG sites.

J. Virol. 86, 447-458 (2012)
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Epstein-Barr virus (EBV) is a human herpesvirus which has been studied intensively for its role in certain human tumors. It also serves as a model of herpesviral latency because it establishes an immediate, latent infection in human B cells. When EBV infe
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Publication type Article: Journal article
Document type Scientific Article
Keywords HEMI-METHYLATED DNA; HUMAN B-CELLS; EPITHELIAL-CELLS; STRUCTURAL BASIS; MAMMALIAN-CELLS; GENE-TRANSFER; SRA DOMAIN; REPLICATION; ACTIVATION; PROTEIN
Language english
Publication Year 2012
HGF-reported in Year 2012
ISSN (print) / ISBN 0022-538X
e-ISSN 1098-5514
Quellenangaben Volume: 86, Issue: 1, Pages: 447-458 Article Number: , Supplement: ,
Publisher American Society for Microbiology (ASM)
Reviewing status Peer reviewed
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Immune Response and Infection
PSP Element(s) G-501500-001
PubMed ID 22031942
Scopus ID 84855980581
Erfassungsdatum 2012-07-23