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Fast scanning coaxial optoacoustic microscopy.
Biomed. Opt. Express 3, 1724-1731 (2012)
The hybrid nature of optoacoustic imaging might impose limitations on concurrent placement of optical and ultrasonic detection components, especially in high resolution microscopic applications that require dense arrangements and miniaturization of components. This hinders optimal deployment of the optical excitation and ultrasonic detection paths, leading to reduction of imaging speed and spatial resolution performance. We suggest a compact coaxial design for optoacoustic microscopy that allows optimizing both the light illumination and ultrasonic detection parameters of the imaging system. System performance is showcased in phantoms and in vivo imaging of microvasculature, achieving real time operation in two dimensions and penetration of 6 mm into optically dense human tissues.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
RESOLUTION PHOTOACOUSTIC MICROSCOPY; IN-VIVO; TOMOGRAPHY
ISSN (print) / ISBN
2156-7085
e-ISSN
2156-7085
Journal
Biomedical Optics Express
Quellenangaben
Volume: 3,
Issue: 7,
Pages: 1724-1731
Publisher
Optical Society of America (OSA)
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)