Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
DOI
PMC
 |
|
Open Access Green as soon as Postprint is submitted to ZB.
Performance assessment and uncertainty evaluation of a portable NaI-based detection system used for thyroid monitoring.
Radiat. Prot. Dosim. 151, 252-261 (2012)
This work aims at assessing the performance of a portable detection system, equipped with an NaI(Tl) scintillation detector for in vivo thyroid monitoring, which was properly calibrated using an anthropomorphic neck phantom. The anthropomorphic physical phantoms commonly used for the efficiency calibration of in vivo counters often present certain limitations regarding the geometry and the activity distribution. Therefore, the feasibility of these detection systems for in vivo monitoring should be assessed whenever possible. To accomplish this assessment, patients to whom (99m)Tc and (123)I marked radiopharmaceuticals have been administered in the framework of nuclear medicine diagnostic procedures were monitored. As the biokinetic models of the administered radiopharmaceuticals are known, the time-dependent activity functions in the critical organs after administration are easily quantified. The measured activities in the thyroid using the NaI(Tl) scintillation detector were compared with the estimated activities using the biokinetic models, in order to reach conclusion about the applicability of the portable scintillation counter for in vivo thyroid monitoring. The state-of-the-art Monte Carlo computer program PENELOPE and two voxel phantoms (male and female) were used to evaluate the overall uncertainties influencing the thyroid monitoring. A computational parametric study was performed to quantify the influence of several parameters in the activity quantification (neck-detector distance, thyroid shape, thyroid size and overlying tissue thickness), which allowed one to gain insight and to better understand the discrepancies between the calculated and measured activities.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Scientific Article
Keywords
in vivo thyroid monitoring; efficiency calibration; portable detection system; portable scintillation counter; uncertainty
ISSN (print) / ISBN
0144-8420
e-ISSN
1742-3406
Journal
Radiation Protection Dosimetry
Quellenangaben
Volume: 151,
Issue: 2,
Pages: 252-261
Publisher
Oxford University Press
Publishing Place
Oxford
Non-patent literature
Publications
Reviewing status
Peer reviewed