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Open Access Green as soon as Postprint is submitted to ZB.
Hybrid system for simultaneous fluorescence and X-Ray computed tomography.
IEEE Trans. Med. Imaging 29, 465-473 (2010)
A hybrid imaging system for simultaneous fluorescence tomography and X-ray computed tomography (XCT) of small animals has been developed and presented. The system capitalizes on the imaging power of a 360 degrees-projection free-space fluorescence tomography system, implemented within a microcomputed tomography scanner. Image acquisition is based on techniques that automatically adjust a series of imaging parameters to offer a high dynamic range dataset. Image segmentation further allows the incorporation of structural priors in the optical reconstruction problem to improve the imaging performance. The functional system characteristics are showcased, and images from a brain imaging study are shown, which are reconstructed using XCT-derived priors into the optical forward problem.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Fluorescence tomography; Hybrid imaging; diffuse optical tomography; molecular tomography; breast-cancer; in-vivo; magnetic-resonance; information; media; reconstruction; noncontact; light
ISSN (print) / ISBN
0278-0062
e-ISSN
1558-254X
Quellenangaben
Volume: 29,
Issue: 2,
Pages: 465-473
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Publishing Place
New York, NY [u.a.]
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)