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Open Access Green as soon as Postprint is submitted to ZB.
Recommendations for the categorization of germ cell mutagens.
Int. Arch. Occup. Environ. Health 73, 428-432 (2000)
Germ cell mutagens are currently classified into three categories in the German List of MAK and BAT Values. These categories have been revised and extended by analogy with the new categories for carcinogenic chemicals. Germ cell mutagens produce heritable gene mutations, and heritable structural and numerical chromosome aberrations in germ cells. The original categories 1 and 2 for germ cell mutagens remain unchanged. Two new categories 3A and 3B are proposed for chemicals suspected to be germ cell mutagens. A new category 5 is proposed for germ cell mutagens with low potency that contribute negligibly to human genetic risk provided the MAK value is observed.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
germ cell mutagens; list of MAK and BAT values; genetic risk
Language
english
Publication Year
2000
HGF-reported in Year
0
ISSN (print) / ISBN
0340-0131
e-ISSN
1432-1246
Quellenangaben
Volume: 73,
Issue: 6,
Pages: 428-432
Publisher
Springer
Reviewing status
Peer reviewed
Institute(s)
Institute of Experimental Genetics (IEG)
Institute of Molecular Toxicology and Pharmacology (TOX)
Institute of Molecular Toxicology and Pharmacology (TOX)
POF-Topic(s)
Research field(s)
Genetics and Epidemiology
PSP Element(s)
FE 70614
PubMed ID
11007348
Erfassungsdatum
2000-12-31