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MitoP2: The mitochondrial proteome database-now including mouse data.
Nucleic Acids Res. 34, D705-D711 (2006)
The MitoP2 database (http://www.mitop.de) integrates information on mitochondrial proteins, their molecular functions and associated diseases. The central database features are manually annotated reference proteins localized or functionally associated with mitochondria supplied for yeast, human and mouse. MitoP2 enables (i) the identification of putative orthologous proteins between these species to study evolutionarily conserved functions and pathways; (ii) the integration of data from systematic genome-wide studies such as proteomics and deletion phenotype screening; (iii) the prediction of novel mitochondrial proteins using data integration and the assignment of evidence scores; and (iv) systematic searches that aim to find the genes that underlie common and rare mitochondrial diseases. The data and analysis files are referenced to data sources in PubMed and other online databases and can be easily downloaded. MitoP2 users can explore the relationship between mitochondrial dysfunctions and disease and utilize this information to conduct systems biology approaches on mitochondria.
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7.552
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
C-OXIDASE DEFICIENCY; SACCHAROMYCES-CEREVISIAE; GLOBAL ANALYSIS; YEAST; PROTEINS; GENOME; EXPRESSION; SCALE; IDENTIFICATION; KNOWLEDGEBASE
Language
english
Publication Year
2006
HGF-reported in Year
0
ISSN (print) / ISBN
0305-1048
e-ISSN
1362-4962
Journal
Nucleic Acids Research
Quellenangaben
Volume: 34,
Issue: SI,
Pages: D705-D711
Publisher
Oxford University Press
Reviewing status
Peer reviewed
Institute(s)
Institute of Human Genetics (IHG)
Institute of Bioinformatics and Systems Biology (IBIS)
Institute of Bioinformatics and Systems Biology (IBIS)
POF-Topic(s)
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
30505 - New Technologies for Biomedical Discoveries
30505 - New Technologies for Biomedical Discoveries
Research field(s)
Genetics and Epidemiology
Enabling and Novel Technologies
Enabling and Novel Technologies
PSP Element(s)
G-500700-001
G-503700-001
G-503700-001
PubMed ID
16381964
WOS ID
000239307700149
Erfassungsdatum
2006-04-04