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Du, Y.* ; Jiang, Q.* ; Bézière, N. ; Song, L.* ; Zhang, Q.* ; Peng, D.* ; Chi, C.L.* ; Yang, X.* ; Guo, H.* ; Diot, G. ; Ntziachristos, V. ; Ding, B.* ; Tian, J.*

DNA-nanostructure-gold-nanorod hybrids for enhanced in vivo optoacoustic imaging and photothermal therapy.

Adv. Mater. 28, 10000-10007 (2016)

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A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.

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18.960

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134

143