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Ditz, B.* ; Boekhoudt, J.G.* ; Aliee, H. ; Theis, F.J. ; Nawijn, M.C.* ; Brandsma, C.A.* ; Hiemstra, P.S.* ; Timens, W.* ; Tew, G.W.* ; Grimbaldeston, M.A.* ; Neighbors, M.* ; Guryev, V.* ; van den Berge, M.* ; Faiz, A.*

Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: Does it provide new insights?

ERJ Open Res. 7:00104-2021 (2021)
Publ. Version/Full Text DOI PMC
Open Access Gold
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More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https://bit.ly/2N8sY3s.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 2021
HGF-reported in Year 2021
ISSN (print) / ISBN 2312-0541
e-ISSN 2312-0541
Journal ERJ Open Research
Quellenangaben Volume: 7, Issue: 2, Pages: , Article Number: 00104-2021 Supplement: ,
Publisher European Respiratory Society
Publishing Place [S.l.]
Reviewing status Peer reviewed
Institute(s) Institute of Computational Biology (ICB)
POF-Topic(s) 30205 - Bioengineering and Digital Health
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-503800-001
DOI 10.1183/23120541.00104-2021
PubMed ID 34164552
Erfassungsdatum 2021-07-29
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