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Wen, B.* ; Wu, Y.* ; Guo, Y.* ; Gasparrini, A.* ; Tong, S.* ; Overcenco, A.* ; Urban, A.* ; Schneider, A.E. ; Entezari, A.* ; Vicedo-Cabrera, A.M.* ; Zanobetti, A.* ; Analitis, A.* ; Zeka, A.* ; Tobias, A.* ; Nunes, B.* ; Alahmad, B.* ; Armstrong, B.* ; Forsberg, B.* ; Pan, S.C.* ; Iñiguez, C.* ; Ameling, C.* ; Valencia, C.C.* ; Åström, C.* ; Houthuijs, D.* ; Van Dung, D.* ; Royé, D.* ; Indermitte, E.* ; Lavigne, E.* ; Mayvaneh, F.* ; Acquaotta, F.* ; de'Donato, F.* ; Rao, S.* ; Sera, F.* ; Carrasco-Escobar, G.* ; Kan, H.* ; Orru, H.* ; Kim, H.* ; Holobaca, I.H.* ; Kyselý, J.* ; Madureira, J.* ; Schwartz, J.* ; Jaakkola, J.J.K.* ; Katsouyanni, K.* ; Diaz, M.H.* ; Ragettli, M.S.* ; Hashizume, M.* ; Pascal, M.* ; Coelho, M.S.Z.S.* ; Ortega, N.V.* ; Ryti, N.* ; Scovronick, N.* ; Michelozzi, P.* ; Matus Correa, P.* ; Goodman, P.* ; Saldiva, P.H.N.* ; Raz, R.* ; Abrutzky, R.* ; Osorio, S.* ; Dang, T.N.* ; Colistro, V.* ; Huber, V.* ; Lee, W.* ; Seposo, X.* ; Honda, Y.* ; Kim, Y.* ; Guo, Y.L.* ; Bell, M.L.* ; Li, S.*

Comparison for the effects of different components of temperature variability on mortality: A multi-country time-series study.

Environ. Int. 187:108712 (2024)
Publ. Version/Full Text DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
BACKGROUND: Temperature variability (TV) is associated with increased mortality risk. However, it is still unknown whether intra-day or inter-day TV has different effects. OBJECTIVES: We aimed to assess the association of intra-day TV and inter-day TV with all-cause, cardiovascular, and respiratory mortality. METHODS: We collected data on total, cardiovascular, and respiratory mortality and meteorology from 758 locations in 47 countries or regions from 1972 to 2020. We defined inter-day TV as the standard deviation (SD) of daily mean temperatures across the lag interval, and intra-day TV as the average SD of minimum and maximum temperatures on each day. In the first stage, inter-day and intra-day TVs were modelled simultaneously in the quasi-Poisson time-series model for each location. In the second stage, a multi-level analysis was used to pool the location-specific estimates. RESULTS: Overall, the mortality risk due to each interquartile range [IQR] increase was higher for intra-day TV than for inter-day TV. The risk increased by 0.59% (95% confidence interval [CI]: 0.53, 0.65) for all-cause mortality, 0.64% (95% CI: 0.56, 0.73) for cardiovascular mortality, and 0.65% (95% CI: 0.49, 0.80) for respiratory mortality per IQR increase in intra-day TV0-7 (0.9 °C). An IQR increase in inter-day TV0-7 (1.6 °C) was associated with 0.22% (95% CI: 0.18, 0.26) increase in all-cause mortality, 0.44% (95% CI: 0.37, 0.50) increase in cardiovascular mortality, and 0.31% (95% CI: 0.21, 0.41) increase in respiratory mortality. The proportion of all-cause deaths attributable to intra-day TV0-7 and inter-day TV0-7 was 1.45% and 0.35%, respectively. The mortality risks varied by lag interval, climate area, season, and climate type. CONCLUSIONS: Our results indicated that intra-day TV may explain the main part of the mortality risk related to TV and suggested that comprehensive evaluations should be proposed in more countries to help protect human health.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Inter-day ; Intra-day ; Mortality ; Temperature Variability; Neighboring Days; Impact; Range; Hospitalization; Vulnerability; Metaanalysis; Association; Health; Brazil
ISSN (print) / ISBN 0160-4120
e-ISSN 1873-6750
Journal Environment International
Quellenangaben Volume: 187, Issue: , Pages: , Article Number: 108712 Supplement: ,
Publisher Elsevier
Publishing Place The Boulevard, Langford Lane, Kidlington, Oxford Ox5 1gb, England
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Epidemiology (EPI)
Grants National Institute of Environmental Health Sciences
Ministry of Science and Technology (Taiwan)
Czech Science Foundation
Emerging Leader Fellowship of the Australian National Health and Medical Research Council
China Scholarship Council
Australian National Health and Medical Research Council
Environment Research and Technology Development Fund of the Environmental Restoration and Conservation Agency
Sao Paulo Research Foundation (FAPESP)
Science and Technology Commission of Shanghai Municipality
MCIN/AEI
Spanish Ministry of Economy, Industry and Competitiveness
EU
Natural Environment Research Council UK
Medical Research Council UK
Fundacao para a Ciencia e a Tecnlogia
EI by the Estonian Ministry of Education and Research
Australian Research Council