Open Access Gold möglich sobald Verlagsversion bei der ZB eingereicht worden ist.
The Ste20 kinase misshapen is essential for the invasive behaviour of ovarian epithelial cells in Drosophila.
EMBO Rep. 11, 943-949 (2010)
Stationary-to-migratory transitions of epithelial cells have a key role in development and tumour progression. Border cell migration is a powerful system in which to investigate this transition in living organisms. Here, we identify the Ste20-like kinase misshapen (msn) as a novel regulator of border-cell migration in Drosophila. Expression of msn in border cells is independent of the transcription factor slow border cells and of inputs from all pathways that are known to control border-cell migration. The msn gene functions to modulate the levels and/or distribution of Drosophila E-cadherin to promote the invasive migratory behaviour of border cells.
Impact Factor
Scopus SNIP
Scopus
Cited By
Cited By
Altmetric
0.000
1.170
20
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2010
HGF-Berichtsjahr
0
ISSN (print) / ISBN
1469-221X
e-ISSN
1469-3178
Zeitschrift
EMBO Reports
Quellenangaben
Band: 11,
Heft: 12,
Seiten: 943-949
Verlag
EMBO Press
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30204 - Cell Programming and Repair
Forschungsfeld(er)
Stem Cell and Neuroscience
PSP-Element(e)
G-500100-001
PubMed ID
21102643
Erfassungsdatum
2010-12-31