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Cannon, S.B.* ; Sterck, L.* ; Rombauts, S.* ; Sato, S.* ; Cheung, F.* ; Gouzy, J.* ; Wang, X.* ; Mudge, J.* ; Vasdewani, J.* ; Schiex, T.* ; Spannagl, M. ; Monaghan, E.* ; Nicholson, C.* ; Humphray, S.J.* ; Schoof, H.* ; Mayer, K.F.X. ; Rogers, J.* ; Quétier, F.* ; Oldroyd, G.E.* ; Debellé, F.* ; Cook, D.R.* ; Retzel, E.F.* ; Roe, B.A.* ; Town, C.D.* ; Tabata, S.* ; van de Peer, Y.* ; Young, N.D.*

Legume genome evolution viewed through the Medicago truncatula and Lotus japonicus genomes.

Proc. Natl. Acad. Sci. U.S.A. 103, 14959-14964 (2006)
Verlagsversion Volltext DOI PMC
Open Access Gold
Genome sequencing of the model legumes, Medicago truncatula and Lotus japonicus, provides an opportunity for large-scale sequence-based comparison of two genomes in the same plant family. Here we report synteny comparisons between these species, including details about chromosome relationships, large-scale synteny blocks, microsynteny within blocks, and genome regions lacking clear correspondence. The Lotus and Medicago genomes share a minimum of 10 large-scale synteny blocks, each with substantial collinearity and frequently extending the length of whole chromosome arms. The proportion of genes syntenic and collinear within each synteny block is relatively homogeneous. Medicago-Lotus comparisons also indicate similar and largely homogeneous gene densities, although gene-containing regions in Mt occupy 20-30% more space than Lj counterparts, primarily because of larger numbers of Mt retrotransposons. Because the interpretation of genome comparisons is complicated by large-scale genome duplications, we describe synteny, synonymous substitutions and phylogenetic analyses to identify and date a probable whole-genome duplication event. There is no direct evidence for any recent large-scale genome duplication in either Medicago or Lotus but instead a duplication predating speciation. Phylogenetic comparisons place this duplication within the Rosid I clade, clearly after the split between legumes and Salicaceae (poplar).
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter polyploidy; synteny; genome duplication; ARABIDOPSIS-THALIANA; PHYLOGENETIC ANALYSIS; DUPLICATE GENES; LINKAGE MAP; MODEL; SEQUENCE; MICROSYNTENY; ALIGNMENT; DATABASE; CROP
Sprache englisch
Veröffentlichungsjahr 2006
HGF-Berichtsjahr 0
ISSN (print) / ISBN 0027-8424
e-ISSN 1091-6490
Quellenangaben Band: 103, Heft: 40, Seiten: 14959-14964 Artikelnummer: , Supplement: ,
Verlag National Academy of Sciences
Begutachtungsstatus Peer reviewed
PSP-Element(e) G-503700-002
PubMed ID 17003129
Erfassungsdatum 2006-10-13