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Dean-Ben, X.L. ; Ma, R. ; Rosenthal, A. ; Ntziachristos, V. ; Razansky, D.

Weighted model-based optoacoustic reconstruction in acoustic scattering media.

Phys. Med. Biol. 58, 5555-5566 (2013)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Model-based optoacoustic inversion methods are capable of eliminating image artefacts associated with the widely adopted back-projection reconstruction algorithms. Yet, significant image artefacts might also occur due to reflections and scattering of optoacoustically-induced waves from strongly acoustically-mismatched areas in tissues. Herein, we modify the model-based reconstruction methodology to incorporate statistically-based weighting in order to minimize these artefacts. The method is compared with another weighting procedure termed half-image reconstruction, yielding generally better results. The statistically-based weighting is subsequently verified experimentally, attaining quality improvement of the optoacoustic image reconstructions in the presence of acoustic mismatches in tissue phantoms and small animals ex-vivo.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Image-reconstruction ; Thermoacoustic Tomography ; Algorithm
Sprache englisch
Veröffentlichungsjahr 2013
HGF-Berichtsjahr 2013
ISSN (print) / ISBN 0031-9155
e-ISSN 1361-6560
Zeitschrift Physics in Medicine and Biology
Quellenangaben Band: 58, Heft: 16, Seiten: 5555-5566 Artikelnummer: , Supplement: ,
Verlag Institute of Physics Publishing (IOP)
Verlagsort Bristol
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)
POF Topic(s) 30205 - Bioengineering and Digital Health
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-505500-001
G-505590-001
PubMed ID 23892587
DOI 10.1088/0031-9155/58/16/5555
WOS ID WOS:000322775300016
Erfassungsdatum 2013-08-13
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