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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Hepatosplenic T-cell lymphoma in a patient with Crohn's disease.
Nat. Rev. Gastroenterol. Hepatol. 6, 433-436 (2009)
BACKGROUND: A 58-year-old man who had a 35-year history of Crohn's disease presented to our IBD center with a disease flare, pararectal fistulas and abscess formation. The patient had previously undergone ileocolic resection for a stenosis and his abscesses had been treated by surgical drainage. He had been taking azathioprine therapy for approximately 5.5 years and had received high-dose steroids. He had also previously taken metronidazole and antihypertensive medications. INVESTIGATIONS: Physical examination, laboratory investigations including hemoglobin levels and white blood cell counts, genetic testing, CT, bone-marrow biopsy, immunophenotyping by fluorescence-activated cell sorting, polymerase chain reaction analyses, fluorescence in situ hybridization, sputum culture and diagnostic splenectomy. DIAGNOSIS: Hepatosplenic T-cell lymphoma. MANAGEMENT: Splenectomy, antibiotic therapy and chemotherapy with cyclophosphamide.
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Anmerkungen
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2009
HGF-Berichtsjahr
0
ISSN (print) / ISBN
1759-5045
e-ISSN
1759-5053
Zeitschrift
Nature Reviews - Gastroenterology & Hepatology
Quellenangaben
Band: 6,
Heft: 7,
Seiten: 433-436
Verlag
Nature Publishing Group
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Molecular Immunology (IMI)
PubMed ID
19575026
Erfassungsdatum
2009-12-31