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    Atemwegsbeschwerden und Sensibilisierungen gegen Pollen von Ambrosia artemisiifolia und Beifuß bei Erwachsenen in Süd-West-Deutschland.
Respiratory symptoms and sensitization to airborne pollen of ragweed and mugwort of adults in Southwest Germany.
        
        Dtsch. Med. Wochenschr. 138, 1651-1658 (2013)
    
    
    
				Background and objective: Allergic diseases of the respiratory tract are common atopic diseases in the population. Pollen of plants are one of their main causes. Pollen of trees, grasses, and weeds like mugwort are of particular importance in this context. The purpose of the present study was to determine the association between typical respiratory symptoms due to pollen allergens and the sensitization to pollen of ragweed and mugwort in adults. Methods: 1039 participants (18 to 66 years) from Southwest Germany were included in this cross-sectional study. Complains typically for aeroallergens were recorded by questionnaire. In-vitro existing sensitizations were determined for grasses/early bloomer (gx1), trees (tx6), mugwort (w6 and Art-v1) and ragweed (w1 and Amb-a1) by testing for specific IgE-antibodies. Results: In a screening test with a mixed allergen sample (sx1) 36.0 % of the participants showed an aeroallergen sensitization. Consecutive investigations of these 374 positive samples revealed a sensitization to grasses/early bloomer, trees, ragweed (w1), mugwort (w6) and the major allergens ragweed (Amb-a1) and mugwort (Art-v1) in 61.8 %, 54.5 %, 29.9 %, 24.3 %, 1.9 %, and 12.3 %, respectively. This corresponds to 22.2 %, 19.6 %, 10.8 %, 8.7 %, 0.7 % and 4.4 %, respectively, in the whole study population. The participants tested positively stated significantly more disorders. On average, 51.1 % had known hay fever, 65.2 % sneezing without cold and 41.5 % sneezing due to contact with grasses or flowers. In contrast, participants tested negatively stated disorders in only 4.4 %, 32.5 %, and 3.9 %, respectively. Conclusion: In Southwest Germany, sensitizations to plant pollen mainly are still caused by grasses, trees, and weeds like mugwort. A sensitization to pollen of ragweed alone is rare until now. However, in case of continuous allergic disorders of the respiratory tract in late summer, a sensitization to ragweed can be important for differential diagnostics.
			
			
		Impact Factor
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Times Cited
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				0.550
					0.293
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
     
    
    
        Schlagwörter
        Ragweed ; Mugwort ; Airborne Pollen ; Sensitization ; Ige ; Allergic Respiratory Diseases; Ambrosia-artemisiifolia L.; Allergic Rhinitis; Cross-reactivity; Atmospheric Co2; North-america; Air-pollution; Asthma; Europe; Prevalence; Profilin
    
 
     
    
    
        Sprache
        deutsch
    
 
    
        Veröffentlichungsjahr
        2013
    
 
     
    
        HGF-Berichtsjahr
        2014
    
 
    
    
        ISSN (print) / ISBN
        0012-0472
    
 
    
        e-ISSN
        1439-4413
    
 
     
     
     
	     
	 
	 
    
        Zeitschrift
        Deutsche Medizinische Wochenschrift - DMW
    
 
		
    
        Quellenangaben
        
	    Band: 138,  
	    Heft: 33,  
	    Seiten: 1651-1658 
	    
	    
	
    
 
  
         
        
            Verlag
            Thieme
        
 
        
            Verlagsort
            Stuttgart
        
 
	
         
         
         
         
         
	
         
         
         
    
         
         
         
         
         
         
         
    
        Begutachtungsstatus
        Peer reviewed
    
 
    
        Institut(e)
        Institute for Allergy Research (IAF)
    
 
    
        POF Topic(s)
        80000 - German Center for Lung Research
    
 
    
        Forschungsfeld(er)
        Allergy	
    
 
    
        PSP-Element(e)
        G-501800-541
    
 
     
     	
    
    
        WOS ID
        WOS:000330538900005
    
    
        Erfassungsdatum
        2014-03-03