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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans.
Stroke 39, 1593-1596 (2008)
Genetic variation in the EPHX2 gene region has been reported to influence susceptibility to ischemic stroke in blacks. We assessed the role of this gene region in white Europeans and performed analyses with regard to stroke subtypes. METHODS: Twenty-six single nucleotide polymorphisms in the EPHX2 gene region were genotyped in 601 patients with ischemic stroke and 736 matched controls. Cases were subtyped according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification system. Analyses were done on single markers and haplotypes using a sliding-window approach. RESULTS: Three single nucleotide polymorphisms showed associations with an increased risk for ischemic stroke (allelic models; all P
Impact Factor
Scopus SNIP
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Times Cited
Times Cited
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6.296
2.760
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
stroke; genetics; EPHX2
Sprache
englisch
Veröffentlichungsjahr
2008
HGF-Berichtsjahr
2008
ISSN (print) / ISBN
0039-2499
e-ISSN
1524-4628
Zeitschrift
Stroke
Quellenangaben
Band: 39,
Heft: 5,
Seiten: 1593-1596
Verlag
Lippincott Williams & Wilkins
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Epidemiology (EPI)
Institute of Human Genetics (IHG)
Institute of Human Genetics (IHG)
POF Topic(s)
30503 - Chronic Diseases of the Lung and Allergies
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-503900-001
G-500700-001
G-500700-001
Scopus ID
44449110695
Erfassungsdatum
2008-10-13