Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Linkage group HL-A-MLC-Bf (properdin factor B) - The site of the Bf locus at the immunogenetic linkage group on chromosome 6.
Hum. Genet. 27, 173-183 (1975)
Genetic linkage between the HL-A and Bf loci could be confirmed in 43 families with 168 offspring. In 4 families, 5 recombinants out of 82 informative meiotic divisions were observed (r=6.1%). The localisation of the Bf marker system was studied in 3 families with crossovers between HL-A and MLC. From these data the following map order of human chromosome 6 can be proposed: HL-A (1st locus) -HL-A (2nd locus)-MLC-Bf---PGM3. The fact that important components of the classical and alternate pathway of complement activation are governed by genes closely linked with HL-A and MLC loci leads to the proposition to include the Bf system into the Major Histocompatibility Complex in man.
Impact Factor
Scopus SNIP
Scopus
Cited By
Cited By
Altmetric
0.000
0.000
64
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
1975
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0340-6717
e-ISSN
1432-1203
Zeitschrift
Human Genetics
Quellenangaben
Band: 27,
Heft: 3,
Seiten: 173-183
Verlag
Springer
Begutachtungsstatus
Peer reviewed
Institut(e)
Institut für Hämatologie
PubMed ID
125222
Scopus ID
0016805714
Erfassungsdatum
1975-01-07