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The use of biomaterials in islet transplantation.
Curr. Diab. Rep. 11, 434-444 (2011)
Pancreatic islet transplantation is a therapeutic option to replace destroyed β cells in autoimmune diabetes. Islets are transplanted into the liver via the portal vein; however, inflammation, the required immunosuppression, and lack of vasculature decrease early islet viability and function. Therefore, the use of accessory therapy and biomaterials to protect islets and improve islet function has definite therapeutic potential. Here we review the application of niche accessory cells and factors, as well as the use of biomaterials as carriers or capsules, for pancreatic islet transplantation.
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Anmerkungen
Besondere Publikation
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2011
HGF-Berichtsjahr
0
ISSN (print) / ISBN
1534-4827
e-ISSN
1539-0829
Zeitschrift
Current Diabetes Reports
Quellenangaben
Band: 11,
Heft: 5,
Seiten: 434-444
Verlag
Springer
Verlagsort
Heidelberg [u.a.]
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
21748257
Erfassungsdatum
2011-12-31