möglich sobald bei der ZB eingereicht worden ist.
Immunogenicity of embryonic stem cells and their progeny.
Methods Enzymol. 420, 391-409 (2006)
The ability of pluripotent human embryonic stem cells (hESCs) to differentiate into multiple cell types has led to great excitement about their potential use in the treatment of various degenerative and malignant human diseases. Before such a goal is attainable, however, it must be demonstrated that pure populations of specialized cell types can be isolated and transplanted while simultaneously avoiding possible immune-mediated rejection of these cells. In this chapter, I will discuss the utility of the humanized mouse Trimera model as an in vivo experimental system to study the immunological properties of hESCs and their differentiated derivatives.
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Anmerkungen
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2006
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0076-6879
e-ISSN
0076-6879
Zeitschrift
Methods in Enzymology
Quellenangaben
Band: 420,
Seiten: 391-409
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Stem Cell Research (ISF)
POF Topic(s)
30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Forschungsfeld(er)
Stem Cell and Neuroscience
PSP-Element(e)
G-552400-001
PubMed ID
17161708
Erfassungsdatum
2006-12-31