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Williams, K.M.* ; Verhoeven, V.J.* ; Cumberland, P.M.* ; Bertelsen, G.* ; Wolfram, C.* ; Buitendijk, G.H.* ; Hofman, A.* ; van Duijn, C.M.* ; Vingerling, J.R.* ; Kuijpers, R.W.* ; Höhn, R.* ; Mirshahi, A.* ; Khawaja, A.P.* ; Luben, R.N.* ; Erke, M.G.* ; von Hanno, T.* ; Mahroo, O.* ; Hogg, R.* ; Gieger, C. ; Cougnard-Grégoire, A.* ; Anastasopoulos, E.* ; Bron, A.* ; Dartigues, J.F.* ; Korobelnik, J.F.* ; Creuzot-Garcher, C.* ; Topouzis, F.* ; Delcourt, C.* ; Rahi, J.S.* ; Meitinger, T. ; Fletcher, A.* ; Foster, P.J.* ; Pfeiffer, N.* ; Klaver, C.C.* ; Hammond, C.J.*

Prevalence of refractive error in Europe: The European Eye Epidemiology (E3) consortium.

Eur. J. Epidemiol. 30, 305-315 (2015)
Verlagsversion DOI PMC
Open Access Hybrid
Creative Commons Lizenzvertrag
To estimate the prevalence of refractive error in adults across Europe. Refractive data (mean spherical equivalent) collected between 1990 and 2013 from fifteen population-based cohort and cross-sectional studies of the European Eye Epidemiology (E(3)) Consortium were combined in a random effects meta-analysis stratified by 5-year age intervals and gender. Participants were excluded if they were identified as having had cataract surgery, retinal detachment, refractive surgery or other factors that might influence refraction. Estimates of refractive error prevalence were obtained including the following classifications: myopia ≤-0.75 diopters (D), high myopia ≤-6D, hyperopia ≥1D and astigmatism ≥1D. Meta-analysis of refractive error was performed for 61,946 individuals from fifteen studies with median age ranging from 44 to 81 and minimal ethnic variation (98 % European ancestry). The age-standardised prevalences (using the 2010 European Standard Population, limited to those ≥25 and <90 years old) were: myopia 30.6 % [95 % confidence interval (CI) 30.4-30.9], high myopia 2.7 % (95 % CI 2.69-2.73), hyperopia 25.2 % (95 % CI 25.0-25.4) and astigmatism 23.9 % (95 % CI 23.7-24.1). Age-specific estimates revealed a high prevalence of myopia in younger participants [47.2 % (CI 41.8-52.5) in 25-29 years-olds]. Refractive error affects just over a half of European adults. The greatest burden of refractive error is due to myopia, with high prevalence rates in young adults. Using the 2010 European population estimates, we estimate there are 227.2 million people with myopia across Europe.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Consortium ; Epidemiology ; Myopia ; Prevalence ; Refractive Error
Sprache englisch
Veröffentlichungsjahr 2015
HGF-Berichtsjahr 2015
ISSN (print) / ISBN 0393-2990
e-ISSN 1573-7284
Zeitschrift European Journal of Epidemiology
Quellenangaben Band: 30, Heft: 4, Seiten: 305-315 Artikelnummer: , Supplement: ,
Verlag Springer
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
Institute of Human Genetics (IHG)
POF Topic(s) 30202 - Environmental Health
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-504091-004
G-500700-001
PubMed ID 25784363
DOI 10.1007/s10654-015-0010-0
Scopus ID 84939983423
Erfassungsdatum 2015-04-15
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