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Bornstein, S.R.* ; Ehrhart-Bornstein, M.*

Ultrastructural evidence for a paracrine regulation of the rat adrenal cortex mediated by the local release of catecholamines from chromaffin cells.

Endocrinology 131, 3126-3128 (1992)

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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.

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The adrenal glands of perfusion fixed rats were investigated by light and electron microscopy. Within the rat adrenal cortex occurred rays and islets of chromaffin cells which were in close contacts with cortical cells on the electron microscopical level. We achieved to catch the process of exocytosis from a chromaffin cell located within the zona glomerulosa in direct apposition with an adrenocortical cell. The documentation of an exocytotic process from a chromaffin cell neighbouring a cortical cell provides direct evidence in support of a paracrine regulation of the cortex mediated by chromaffin cells.

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