Markmann, J.F.* ; Bartlett, S.T.* ; Johnson, P.* ; Korsgren, O.* ; Hering, B.J.* ; Scharp, D.* ; Kay, T.W.* ; Bromberg, J.* ; Odorico, J.S.* ; Weir, G.C.* ; Bridges, N.D.* ; Kandaswamy, R.* ; Stock, P.* ; Friend, P.* ; Gotoh, M.* ; Cooper, D.K.* ; Park, C.G.* ; OʼConnell, P.J.* ; Stäbler, C.* ; Matsumoto, S.* ; Ludwig, B. ; Choudhary, P.* ; Khovatchev, B.* ; Rickels, M.R.* ; Sykes, M.* ; Wood, K.* ; Kraemer, K.* ; Hwa, A.* ; Stanley, E.* ; Ricordi, C.* ; Zimmerman, M.* ; Greenstein, J.* ; Montanya, E.* ; Otonkoski, T.*
     
 
    
        
Executive summary of IPITA-TTS opinion leaders report on the future of β-cell replacement.
    
    
        
    
    
        
        Transplantation 100, E25-E31 (2016)
    
    
    
		
		
			
				The International Pancreas and Islet Transplant Association (IPITA), in conjunction with the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.
			
			
				
			
		 
		
			
				
					
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
    
        Typ der Hochschulschrift
        
    
 
    
        Herausgeber
        
    
    
        Schlagwörter
        Porcine Islet Xenotransplantation; Mediated Inflammatory Reaction; Nonhuman-primates; Cynomologus Monkeys; Pig Islets; Reversal; Transplantation; Survival; Immunosuppression; Autoimmunity
    
 
    
        Keywords plus
        
    
 
    
    
        Sprache
        englisch
    
 
    
        Veröffentlichungsjahr
        2016
    
 
    
        Prepublished im Jahr 
        
    
 
    
        HGF-Berichtsjahr
        2016
    
 
    
    
        ISSN (print) / ISBN
        0041-1337
    
 
    
        e-ISSN
        1534-0608
    
 
    
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	    Band: 100,  
	    Heft: 7,  
	    Seiten: E25-E31 
	    Artikelnummer: ,  
	    Supplement: ,  
	
    
 
  
        
            Reihe
            
        
 
        
            Verlag
            Lippincott Williams & Wilkins
        
 
        
            Verlagsort
            Philadelphia
        
 
	
        
            Tag d. mündl. Prüfung
            0000-00-00
        
 
        
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            weitere Inhaber
            
        
 
        
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        Begutachtungsstatus
        Peer reviewed
    
 
    
        Institut(e)
        Institute of Pancreatic Islet Research (IPI)
    
 
    
        POF Topic(s)
        90000 - German Center for Diabetes Research
    
 
    
        Forschungsfeld(er)
        Helmholtz Diabetes Center
    
 
    
        PSP-Element(e)
        G-502600-007
    
 
    
        Förderungen
        
    
 
    
        Copyright
        
    
 	
    
    
    
    
        Erfassungsdatum
        2016-04-18