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Heinrich, J. ; Feng, G.* ; Trepka, M.J.*

Low-level mercury exposure and risk of Asthma in school-age children.

Epidemiology 28, 116-118 (2017)
Postprint DOI PMC
Open Access Green
BACKGROUND: Although mercury exposure has been associated with several adverse health effects, the association with childhood asthma is under-investigated. Therefore, we explore the association between mercury and childhood asthma in a population with low mercury levels. METHODS: Mercury levels were measured in blood and urine in 1,056 children aged 5-14 years. In addition to including questions about asthma diagnosis and wheezing, the study measured bronchial hyper-responsiveness and allergic sensitization to common aeroallergens. Logistic regression analysis adjusted for major potential confounders. RESULTS: Overall the adjusted odds ratios (aOR) between log blood mercury and the outcomes were 0.8 (95% CI 0.63, 1.11) for asthma, 0.9 (95% CI 0.79, 1.14) for wheeze, 1.1 (95% CI 0.60, 2.03) for bronchial hyperresponsiveness, and 1.0 (95% CI 0.80, 1.17) for allergic sensitization. Urine mercury adjusted for creatinine was also not associated with any of these allergy-related outcomes. CONCLUSIONS: While the results did not support an association between mercury exposure and asthma, studies are needed to assess prenatal and lifetime exposure to mercury and asthma.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Health; Germany
Sprache
Veröffentlichungsjahr 2017
Prepublished im Jahr 2016
HGF-Berichtsjahr 2016
ISSN (print) / ISBN 1044-3983
e-ISSN 1531-5487
Zeitschrift Epidemiology
Quellenangaben Band: 28, Heft: 1, Seiten: 116-118 Artikelnummer: , Supplement: ,
Verlag Lippincott Williams & Wilkins
Verlagsort Philadelphia
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)
POF Topic(s) 30503 - Chronic Diseases of the Lung and Allergies
Forschungsfeld(er) Genetics and Epidemiology
PSP-Element(e) G-503900-001
DOI 10.1097/EDE.0000000000000576
WOS ID WOS:000390252100026
PubMed ID 27755278
Erfassungsdatum 2016-10-24
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