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Hofweber, M.* ; Hutten, S.* ; Bourgeois, B.* ; Spreitzer, E.* ; Niedner-Boblenz, A. ; Schifferer, M.* ; Ruepp, M.D.* ; Simons, M.* ; Niessing, D. ; Madl, T.* ; Dormann, D.*

Phase separation of FUS is suppressed by its nuclear import receptor and arginine methylation.

Cell 173, 706-719.e13 (2018)
Verlagsversion Forschungsdaten DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Purpose of Review Advances in technology have expanded telemedicine opportunities covering medical practice, research, and education. This is of particular importance in movement disorders (MDs), where the combination of disease progression, mobility limitations, and the sparse distribution of MD specialists increase the difficulty to access. In this review, we discuss the prospects, challenges, and strategies for telemedicine in MDs.Recent Findings Telemedicine for MDs has been mainly evaluated in Parkinson's disease (PD) and compared to in-office care is cost-effective with similar clinical care, despite the barriers to engagement. However, particular groups including pediatric patients, rare MDs, and the use of telemedicine in underserved areas need further research.Summary Interdisciplinary telemedicine and tele-education for MDs are feasible, provide similar care, and reduce travel costs and travel time compared to in-person visits. These benefits have been mainly demonstrated for PD but serve as a model for further validation in other movement disorders.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Als ; Ftd ; Karyopherin-β2 (kapβ2) ; Transportin (tnpo1) ; Arginine Methylation ; Fused In Sarcoma (fus) ; Neurodegeneration ; Nuclear Import ; Phase Separation ; Stress Granules; Randomized Controlled-trial; Chronic Tic Disorders; Parkinsons-disease; Health-care; Tourette-syndrome; Behavior-therapy; Neurological Disorders; Huntington Disease; Batten-disease; Virtual Visits
Sprache
Veröffentlichungsjahr 2018
HGF-Berichtsjahr 2018
ISSN (print) / ISBN 0092-8674
e-ISSN 1097-4172
Zeitschrift Cell
Quellenangaben Band: 173, Heft: 3, Seiten: 706-719.e13 Artikelnummer: , Supplement: ,
Verlag Cell Press
Verlagsort Cambridge, Mass.
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Structural Biology (STB)
POF Topic(s) 30203 - Molecular Targets and Therapies
Forschungsfeld(er) Enabling and Novel Technologies
PSP-Element(e) G-503091-001
DOI 10.1016/j.cell.2018.03.004
WOS ID WOS:000430677400019
Scopus ID 85045120263
PubMed ID 29677514
Erfassungsdatum 2018-06-22
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