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Javier, A.M.* ; Kreft, O.* ; Semmling, M.* ; Kempter, S.* ; Skirtach, A.G.* ; Bruns, O.T. ; del Pino, P.* ; Bedard, M.F.* ; Rädler, J.* ; Käs, J.* ; Plank, C.* ; Sukhorukov, G.B.* ; Parak, W.J.*

Uptake of colloidal polyelectrolyte-coated particles and polyelectrolyte multilayer capsules by living cells.

Adv. Mater. 20, 4281-4287 (2008)

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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.

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Uptake of colloidal polyelectrolyte-coated particles and polyelectrolyte multilayer capsules has been demonstrated by living cells. The capsules for this study were prepared by poly(diallyldimethylammoniumchloride) (PDMAC) and poly(styrene sulfonate) (PSS) on SiO2. SiO2 template cores were used because of their negative charge. It was observed during the study that SiO2 templates dissolved in hydrofluoric acid after the formation of capsule-shell. The study also found that heat treatment can be used for stable encapsulation of materials inside the microcapsuels made on SiO 2. It was also found that calcium carbonate microparticles can provide a loading capacity for biological materials. The study used a confocal laser scanning microscopy (CLSM) to examine the capsule incorporation by the cells.

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