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"Novel" triggers of herpesvirus reactivation and their potential health relevance.
Front. Microbiol. 9:3207 (2019)
© 2019 Stoeger and Adler. After primary infection, herpesviruses persist for life in their hosts in a latent stage (Adler et al., 2017). Different subfamilies of herpesviruses establish latency in specific and different sets of cells (Pellett and Roizman, 2013; Lieberman, 2016). The latent stage can be interrupted by periods of lytic replication, termed reactivation. Reactivation is important for viral spread to new hosts or for the maintenance of the viral reservoir in the host. Usually, reactivation is not associated with disease but under certain circumstances, it may be accompanied by clinical symptoms. The stimuli and the precise molecular mechanisms that lead to reactivation from the latent state are not fully understood and can differ from one herpesvirus to another.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
4.259
1.227
13
11
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Health Relevance ; Herpesvirus ; Nanoparticle ; Non-canonical Triggers ; Reactivation; Cytomegalovirus Latency; Infection
Sprache
englisch
Veröffentlichungsjahr
2019
HGF-Berichtsjahr
2019
ISSN (print) / ISBN
1664-302X
e-ISSN
1664-302X
Zeitschrift
Frontiers in Microbiology
Quellenangaben
Band: 9,
Artikelnummer: 3207
Verlag
Frontiers
Verlagsort
Avenue Du Tribunal Federal 34, Lausanne, Ch-1015, Switzerland
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Lung Health and Immunity (LHI)
Research Unit Lung Repair and Regeneration (LRR)
Research Unit Lung Repair and Regeneration (LRR)
POF Topic(s)
30202 - Environmental Health
80000 - German Center for Lung Research
80000 - German Center for Lung Research
Forschungsfeld(er)
Lung Research
PSP-Element(e)
G-505000-001
G-503100-005
G-501800-311
G-503100-005
G-501800-311
WOS ID
WOS:000455002400001
Scopus ID
85064397010
PubMed ID
30666238
Erfassungsdatum
2019-02-27