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Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles.
Opt. Lett. 34, 2566-2568 (2009)
We report on a systematic study of upconverting fluorescence signal generation within turbid
phantoms and real tissues. An accurate three-point Green's function, describing the forward model
of photon propagation, is established and experimentally validated. We further demonstrate, for the
first time to our knowledge, autofluorescence-free transillumination imaging of mice that have
received biocompatible upconverting nanoparticles. The method holds great promise for artifact-free
whole-body visualization of optical molecular probes.
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Anmerkungen
Besondere Publikation
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2009
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0146-9592
e-ISSN
1539-4794
Zeitschrift
Optics Letters
Quellenangaben
Band: 34,
Heft: 17,
Seiten: 2566-2568
Verlag
Optical Society of America (OSA)
Begutachtungsstatus
Peer reviewed
POF Topic(s)
30205 - Bioengineering and Digital Health
Forschungsfeld(er)
Enabling and Novel Technologies
PSP-Element(e)
G-505500-001
Erfassungsdatum
2009-12-31