PuSH - Publikationsserver des Helmholtz Zentrums München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Khan Mirzaei, M. ; Xue, J. ; Costa, R. ; Ru, J. ; Schulz, S. ; Taranu, Z.E.* ; Deng, L.

Challenges of studying the human virome – relevant emerging technologies.

Trends Microbiol. 29, 171-181 (2021)
Verlagsversion DOI
Open Access Hybrid
Creative Commons Lizenzvertrag
In this review we provide an overview of current challenges and advances in bacteriophage research within the growing field of viromics. In particular, we discuss, from a human virome study perspective, the current and emerging technologies available, their limitations in terms of de novo discoveries, and possible solutions to overcome present experimental and computational biases associated with low abundance of viral DNA or RNA. We summarize recent breakthroughs in metagenomics assembling tools and single-cell analysis, which have the potential to increase our understanding of phage biology, diversity, and interactions with both the microbial community and the human body. We expect that these recent and future advances in the field of viromics will have a strong impact on how we develop phage-based therapeutic approaches.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
17.079
3.727
12
22
Tags
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern

Zusatzinfos bearbeiten
Eigene Tags bearbeiten
Privat
Eigene Anmerkung bearbeiten
Privat
Auf Publikationslisten für
Homepage nicht anzeigen
Als besondere Publikation
markieren
Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
Schlagwörter Bacteriophages ; Computational Tools ; Host Range ; Human Virome ; Multi-omics ; Phage De Novo Discoveries
Sprache englisch
Veröffentlichungsjahr 2021
Prepublished im Jahr 2020
HGF-Berichtsjahr 2020
ISSN (print) / ISBN 0966-842X
e-ISSN 1878-4380
Zeitschrift Trends in microbiology
Quellenangaben Band: 29, Heft: 2, Seiten: 171-181 Artikelnummer: , Supplement: ,
Verlag Cell Press
Verlagsort Cambridge, Mass.
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Virology (VIRO)
POF Topic(s) 30203 - Molecular Targets and Therapies
Forschungsfeld(er) Immune Response and Infection
PSP-Element(e) G-554300-001
Förderungen European Research Council
German Reaserch Foundation (DFG Emmy Noether program)
DOI 10.1016/j.tim.2020.05.021
WOS ID WOS:000614460800010
Scopus ID 85087308722
Erfassungsdatum 2020-07-09
[➜Korrektur melden]